This is the main software I use for illustrating and animating especially with animations that involve more frame by frame actions. I find that this software is very convenient and specially caters to more illustration based projects.

Photoshop is a staple software and is the first one I started illustrating with. I'd say I have a 9 out of 10 grasp of using this software. This is also where I compile the frames I animate for 2d game sprites.

My grasp of Unity is not at the level of coding or scripting. Animating for a 2d game taught me how to add my sprites, slice them accordingly and change the animation timing based on my correspondence with the developer.